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DAR No 2: Vazkepa®. Icosapent Ethil (Omega-3) for hypertriglyceridemia
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- DAR No 1: Nilemdo® / Nustendi®. Bempedoic Acid and Bempedoic Acid/Ezetimibe for hipercholesterolaemia
- DAR No 2: Vazkepa®. Icosapent Ethil (Omega-3) for hypertriglyceridemia
Dubious benefit/risk balance. It doesn’t add up.
Difficult to establish clinical benefit and place in therapy due to the absence of comparative studies, the limitations of the trial (highly selected population not optimized with statins and/or ezetimibe and use of a non-inert placebo) and the increased risk of fibrillation and atrial flutter and bleeding.
